Physiological Functions Folate (folacin or folic acid) participates as a coenzyme in reactions that require transfer of a single carbon moiety in different oxidative states as either a methenyl, methylene, or methyl group. These reactions typically involve synthesis of compounds such as thymidine, a pyrimidine base necessary for synthesis of DNA. In the absence of [...]
Continue reading...Monday, October 19, 2009
Physiological Functions Thiamin is a coenzyme in two reactions involved in oxidative metabolism of glucose. The vitamin works in tandem with other niacin and riboflavin in glucose oxidation to yield useful metabolic energy in the form of ATP. Because nervous tissue is dependent solely on glucose for energy, these tissues are most sensitive to the [...]
Continue reading...Monday, October 19, 2009
Physiologic Functions Biotin coenzyme participates in carboxylation reactions as a carrier of carbon dioxide and donor of carboxyl groups to substrates. The carboxylation step is rate-limiting in fatty acid synthesis. Carboxylation steps are also required in conversion of pyruvate to oxaloacetate which drives the Kreb’s cycle, in metabolism of odd chain fatty acids by converting [...]
Continue reading...
Monday, October 19, 2009
1 Comment